Darvocet FDA Ban Urged

March 2006

The Food and Drug Administration (FDA) is under pressure to ban a pain reliever blamed for more than 2,000 deaths. Darvocet, also known as Darvon, provides poor pain relief at a significant risk, claims the Public Citizen consumer group. They are calling for the FDA to pull it from the market.

Public Citizen’s petition cited 2,110 accidental deaths linked to the drug from 1981 to 1999 and suggested that three times as many may have died. The drug is said to be a risky pain reliever due to the way it breaks down during metabolism, producing norpropoxyphene (NPX). NPX lasts longer in the blood than its parent compound and is extremely toxic. Use of the drug can lead to heart problems and can also damage the nervous system, resulting in falls.

Most of the deaths were people taking Darvocet for long periods of time. A representative of the Citizen Group states that the drug is one of the leading causes of drug-related deaths in the elderly.

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